Bios Line VitaCalm Ansistop ACT sublingual spray

Bios Line VitaCalm Ansistop ACT is a sublingual spray dietary supplement designed to manage stress and anxiety. It is manufactured in Italy by Bios Line S.p.A., a company headquartered in Ponte San Nicolò, near Padua.

Bios Line was founded in 1986 by Paolo Tramonti who combined traditional herbal medicine with modern scientific research. The brand focuses on natural well-being, creating products based on plant extracts. In 2021, the company saw a significant change in its ownership structure when Palladio Holding (PFH), an Italian investment firm, acquired a majority stake in the company. As of 2026, the company continues to operate under the umbrella of Bios Line Holding with its primary manufacturing and research facilities located in the Veneto region of Italy.