Alka-Seltzer Plus Cold & Flu Day/Night relief

Alka-Seltzer Plus is a major line of over-the-counter (OTC) medications used to treat symptoms of the common cold and influenza. The brand is part of the broader Alka-Seltzer family, which was originally developed by Miles Laboratories in 1931 in Elkhart, Indiana, USA. Following the acquisition of Miles Laboratories by the German pharmaceutical giant Bayer AG in 1978, the brand became a flagship product for Bayer’s consumer health division.

Today, Alka-Seltzer Plus products are distributed globally but have a particularly strong presence in North America. While the brand has its roots in the United States, manufacturing is carried out in multiple locations across Bayer's global supply chain to meet international demand. Bayer AG, the ultimate owner, is headquartered in Leverkusen, Germany, and continues to manage the brand as a key component of its Consumer Health segment, often marketing it through its American subsidiary, Bayer HealthCare LLC.