E45 Eczema Repair Cream

Brand History and Evolution

E45 was originally created in 1952 by Crookes Healthcare, a subsidiary of the British pharmaceutical company Boots. It was initially developed as a single product—E45 Cream—designed specifically for hospital use to treat pruritus and sensitive skin. For decades, it remained a medical staple before becoming available to the general public in the early 1980s, eventually growing into a leading name in dermatological care.

Ownership and Global Presence

For many years, E45 was part of the Reckitt Benckiser (Reckitt) portfolio. However, in a significant strategic shift, the brand was acquired by Karo Healthcare in 2022. Karo Healthcare, headquartered in Sweden, is a leading consumer healthcare company that focuses on everyday healthcare products. This acquisition has allowed E45 to expand its specialized product range, including the Eczema Repair line.

Manufacturing and Distribution

E45 products are manufactured in multiple locations across Europe to meet international demand. While the brand maintains its British heritage and strong presence in the UK market, the production facilities are distributed to optimize supply chains across the continent. Karo Healthcare continues to position the brand as a dermatologically-backed solution for dry and compromised skin barriers worldwide.