Advantan 0.1% cream

Advantan is a pharmaceutical brand specializing in topical corticosteroid treatments, containing the active ingredient methylprednisolone aceponate. It is used to treat various inflammatory skin conditions such as eczema and dermatitis. The brand has historical roots in Germany, originally developed by Schering AG, a major pharmaceutical company based in Berlin.

Following a series of corporate acquisitions, the brand became part of Beyer, and eventually, the dermatological portfolio was acquired by LEO Pharma. Today, manufacturing for the Italian market and several other regions typically takes place in Italy (specifically at plants in Segrate), though it is distributed globally. LEO Pharma, headquartered in Denmark, remains the ultimate owner and global distributor of the product as of 2024 and beyond.