Alka-Seltzer XS effervescent tablets

Alka-Seltzer is a globally recognized brand of effervescent pharmaceutical products. It was originally developed in 1931 by Maurice Treneer, a chemist at the Miles Medical Company located in Elkhart, Indiana, USA. The product became famous for its characteristic fizzing action and its 'Plop, plop, fizz, fizz' marketing campaign.

Today, the brand is owned by Bayer, a German multinational pharmaceutical and life sciences company. Bayer acquired the brand in 1978 as part of its acquisition of Miles Laboratories. Alka-Seltzer XS is a specific formula variation often found in the UK and European markets, containing aspirin, paracetamol, and caffeine for double-action pain relief. While the brand is German-owned, manufacturing occurs in various facilities globally to serve different regional markets.