Dicloreum 150 mg prolonged-release capsules

Dicloreum is a well-known brand of diclofenac sodium, a nonsteroidal anti-inflammatory drug (NSAID) primarily used to manage pain and inflammation in conditions like rheumatism and osteoarthritis. The brand belongs to Alfasigma, one of the leading pharmaceutical companies in Italy. The specific version shown is the 150 mg prolonged-release formulation, designed for gradual release of the active ingredient over time.

Alfasigma was formed in 2015 through the merger of two historic Italian pharmaceutical entities: Alfa Wassermann and Sigma-Tau. The company's roots date back to 1948 when Marino Golinelli founded Biochimici Alfa in Bologna. Today, Alfasigma remains a private company under the majority control of the Golinelli family.

Manufacturing for Dicloreum is largely concentrated in Italy at Alfasigma's specialized production sites in locations such as Alanno, Pomezia, and Sermoneta. However, as an international group with a presence in over 100 markets, the company also operates manufacturing facilities in Spain and the United States, and utilizes partners for distribution and production in various other regions.