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Red Cross brand toothache relief products have a long-standing history in the American over-the-counter dental care market. Originally developed by the Mentholatum Company, which was founded in 1889 in Wichita, Kansas, the brand has focused on providing therapeutic solutions for oral pain using ingredients like Eugenol (clove oil).
In 1988, the Mentholatum Company was acquired by Rohto Pharmaceutical Co., Ltd., a major Japanese healthcare company based in Osaka. Today, the manufacturing of these kits typically takes place in the United States to serve the North American consumer market. Rohto continues to manage the brand as part of its global portfolio of health and wellness products, maintaining the traditional medicinal branding associated with the Red Cross name in the dental category.
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