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E45 is a renowned skincare brand with deep roots in British dermatological history. Originally developed in 1952 by Crookes Healthcare, a subsidiary of Boots, it was initially intended as a treatment for dry and itchy skin in a clinical setting. Over decades, it transitioned from a pharmacy-only treatment to a leading household name for eczema and sensitive skin care.
The brand underwent a major ownership change in early 2022 when Karo Healthcare, a Swedish-based consumer healthcare company, acquired E45 from Reckitt Benckiser for approximately £440 million. Today, E45 products are manufactured across multiple locations globally to meet international demand, maintaining their reputation for hypoallergenic and clinically proven formulations. Karo Healthcare, backed by the private equity firm EQT, continues to expand the brand's reach across Europe and beyond.
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